Gary Kubiak gave his input to ESPN.com about what they are looking for in the #15 overall pick, Amobi Okoye, and Duane Brown.
Kubes said they will not go with a receiver or running back in the first round, so you might as well cross off Beanie Wells from your first round mocks. I would guess we won't go with either of those two positions in round two unless there is a can't miss (Beanie or Knowshon drop). My guess is round 3 or one of the round 4 picks will be used to address RB and we might see a later round receiver as well.
Also gathered from this article it seems LB or DB is the pick in round 1. You can say the odd man out is round 2. It seems Smith and Cody have filled voids for the DL and we might go there in round 3.