This is big. Kalu was quietly having an awesome season and was a big reason the defensive line has looked as good as it has. No word on who will start in Kalu's stead, but needless to say the pressure on Super Mario & Co. has ratcheted up a couple of notches.
In related injury news, it looks almost certain that both Ahman Green and Jerome Mathis aren't playing either. If Mathis can't go, Kubes appears to be leaning toward elevating Harry Williams or the newly-signed Devin Aromashodu to provide depth at WR.